Sheen attended Santa Monica High School, where his two major interests were acting and baseball. His friends in school included Rob Lowe and Sean Penn, and with them, he filmed over 200 amateur Super-8 films. He was a pitcher for the baseball team, and his fastest pitch was 84 mph. A few weeks before graduation, Sheen was expelled from the school for poor grades and bad attendance.
Sheen began acting in 1974 at the age of nine, appearing in a small role alongside his father in the TV movie The Execution of Private Slovik. Sheen's film career began in 1984, and his first major role was in Platoon (1986). In 1987, he starred with his father, Martin, in Wall Street. In 2000, Sheen played himself in the comedy Being John Malkovich.
In 2001 and 2002 Sheen played the lead role in the political television sitcom, Spin City (as Michael J. Fox's replacement on that show). In 2002 he won the Golden Globe Award for "Best Performance by an Actor in a Television Series - Musical or Comedy" for this role. Currently Sheen plays the role of Charlie on the sitcom Two and a Half Men, which debuted in 2003.
Sheen was the 2004 spokesperson for the Lee National Denim Day breast cancer fundraiser that raised millions of dollars for research and education regarding the disease. Sheen stated that a friend of his died due to breast cancer, and he wanted to try to help find a cure for the disease.
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